In 2006, 17-year-old O'Pry was scouted from his prom photos on MySpace by Nolé Marin; fashion-icon, model-maker, TV personality and past judge from America's Next Top Model. Bert Hamilton, a photographer from Sean's home state of Georgia, took the picture featured on this article before his career took off.
Since then, O'Pry has been featured in numerous advertising campaigns and editorials for Calvin Klein, Giorgio Armani, Dolce & Gabbana, Gianfranco Ferré, H&M, Marc Jacobs, Emporio Armani, Lacoste, Dsquared2, American Eagle, Bottega Veneta, DKNY, Fendi, GQ, Dazed & Confused, V, Details, Barneys, Uniqlo, Bloomingdale's, Belstaff, D2, Arena, Diesel, Gap, JOOP! and Numéro Homme. He is currently the face of Bottega Veneta and Zara.
His runway credentials include opening Versace, Yves Saint Laurent, Givenchy and Salvatore Ferragamo, and closing Moschino, Trussardi and Zegna. Other designers he has walked for include Roberto Cavalli, Louis Vuitton and Hermes.
He is currently the second most successful male model in the world behind Baptiste Giabiconi on models.com list of the Top 50 international male models, as of June 2010. He has held this position for three years, and was previously ranked behind Mathias Lauridsen. In June 2009, he was named the world's most successful male model of 2009 by Forbes publications. Previously, he was named the world's eighth most successful male model of 2008 by the same magazine.
He was the face of Calvin Klein for several seasons and is best known for being GQ's Man of the Season in 2007.
some people are just lucky...